FINGOLIMOD FOR MULTIPLE SCLEROSIS AND EMERGING INDICATIONS: APPROPRIATE PATIENT SELECTION, SAFETY PRECAUTIONS, AND SPECIAL CONSIDERATIONS

Fingolimod for multiple sclerosis and emerging indications: appropriate patient selection, safety precautions, and special considerations

Ilya Ayzenberg, Robert Hoepner, Ingo Kleiter Department of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany Abstract: Fingolimod (FTY720), an immunotherapeutic drug targeting the sphingosine-1-phosphate receptor, is a widely used medication for relapsing-remitting multiple sclerosis (MS).Apart from the Latest Product Releases &

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Selection of reference genes for quantitative real-time PCR normalization in the plant pathogen Puccinia helianthi Schw.

Abstract Background Real-time RT-PCR has become a common and robust technique to detect and quantify low-abundance mRNA expression and is a prefered tool when examining fungal gene expression in infected host tissues.However, correct evaluation of gene expression data requires accurate and reliable normalization against a reference transcript.Thus,

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IgA Vasculitis Following ChAdOx1 nCoV-19 Vaccination

IgA vasculitis (IgAV), a caruso milk thistle small-vessel vasculitis, is more frequently seen in children than in adults.IgAV is triggered by various bacterial and viral infective agents.Here, we are describing a case of IgAV following ChAdOx1 nCoV-19 vaccination.A 39-year-old male presented with skin rash, joint pain, and pain abdomen.Symptoms sta

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